Eight.6 Hepatic Impairment The pharmacokinetics of hydromorphone are afflicted by hepatic impairment. Because of elevated exposure of hydromorphone, patients with moderate hepatic impairment ought to be started out at one particular-fourth to at least one-half the advisable starting up dose based on the diploma of hepatic dysfunction and closely monitored https://williamq336tcb6.wikilinksnews.com/user