CRISPR-Cas is a powerful genome editing technology and has a great potential for in vivo gene therapy. Successful translational application of CRISPR-Cas to biomedicine still faces many safety concerns. including off-target side effect. cell fitness problem after CRISPR-Cas treatment. https://www.bekindtopets.com/hot-find-Synovex-One-Grass-Extended-Release-Implant-10-Dose-special-find/