In this article, we show that conolidine, a purely natural analgesic alkaloid used in classic Chinese medication, targets ACKR3, thus supplying more evidence of the correlation concerning ACKR3 and discomfort modulation and opening choice therapeutic avenues for that treatment of chronic ache. In such cases, it boosts the Conolidine’s https://www.proleviate.com/post/is-conolidine-a-real-pain-reliever