Allergic reactions to Substances. People who find themselves allergic to any of the following should not get clonidine. Clonidine treats substantial blood pressure level by stimulating αtwo receptors during the brainstem, which decreases peripheral vascular resistance, lowering blood pressure level. It's specificity in the direction of the presynaptic α2 https://www.proleviate.com/post/the-new-pain-killer-conolidine